Louis s goodman biography

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    Contact
    Louis Goodman
    () (Office)
    SIS | Environment, Development & Health
    School of International Service
    by appointment
    Additional Positions at AU
    Affiliate Professor of Sociology
    Degrees
    PhD, Northwestern University; MA, Northwestern University; BA, Dartmouth College
    Doctor Honoris Causa, Ritsumeikan University (Kyoto), University for Peace (San Jose, Costa Rica), San Martin de Porres (Lima)
    Languages Spoken
    Spanish
    Favorite Spot on Campus
    the tennis courts
    Book Currently Reading
    <i>Waging Peace: How Eisenhower Shaped an Enduring Cold War Strategy</i>
    Bio
    Louis Goodman carries out research on social change and politics in Latin America and in Asia. His current research focuses on public goods, regional alliances and development. He has published widely on civil-military relations in Latin amerika, on foreign investment in developing countries and on determinants of career success for blue-collar workers. He has researched and liv

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    Archives West Finding Aid

    Louis S. Goodman () was born August 27 in Portland, Oregon. He graduated from Reed College in , earned his medical degree at the University of Oregon in and interned at Johns Hopkins Hospital before moving to Yale University to study and later teach pharmacology. During World War II, while investigating chemical warfare, Goodman and fellow Yale forskare Dr. Alfred Gilman discovered the effectiveness of nitrogen mustard as an anticancer chemotherapy, a breakthrough which led to chemotherapy's role as a major cancer treatment.

    In , Goodman left Yale for the University of Vermont, and, in he moved to krydda Lake City to become the founding chairman of the Department of Pharmacology at the University of Utah's School of medicin. There, he supervised experiments in anesthesia with the paralyzing muscle relaxant, curare, once used bygd South American Indians as poison.

    A particular authority on drugs for treating both cancer and epileptic seizures, Goodman creat

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    Mouse Lymphoma

    The remarkable sensitivity and vulnerability of rapidly proliferating cells and lymphoid tissues suggested that the mustards might effectively treat lymphoid tumors. Goodman and Gilman showed their rabbit data to Thomas Dougherty, a Yale anatomy professor, and he agreed to assist with the first efficacy studies.16,19

    Sulfur mustard had undesirable physical properties for these studies.16 It was volatile, quite insoluble, unstable in water, dangerous to handle and difficult to administer.17

    The nitrogen mustard analogs were slightly less reactive than sulfur mustard.16,21 They formed non-volatile, water-soluble hydrochloride salts, could be handled safely, and could be administered intravenously.16,17

    In the first series of experiments, they injected mice to determine the acute lethal dose and the dose that could be given daily without drastically affecting bone marrow.19

    By chance, Dougherty had implanted a mouse with lymphoma, and the tumor was fai